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KMID : 0383820140770050223
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Tuberculosis and Respiratory Diseases
2014 Volume.77 No. 5 p.223 ~ p.226
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Aspergillus Tracheobronchitis in a Mild Immunocompromised Host
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Cho Byung-Ha
Oh Young-Min
Kang Eun-Seok
Hong Yong-Joo
Jeong Hye-Won
Lee Ok-Jun
Chang You-Jin
Choe Kang-Hyeon
Lee Ki-Man
An Jin-Young
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Abstract
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Aspergillus tracheobronchitis is a form of invasive pulmonary aspergillosis in which the Aspergillus infection is limited predominantly to the tracheobronchial tree. It occurs primarily in severely immunocompromised patients such as lung transplant recipients. Here, we report a case of Aspergillus tracheobronchitis in a 42-year-old man with diabetes mellitus, who presented with intractable cough, lack of expectoration of sputum, and chest discomfort. The patient did not respond to conventional treatment with antibiotics and antitussive agents, and he underwent bronchoscopy that showed multiple, discrete, gelatinous whitish plaques mainly involving the trachea and the left bronchus. On the basis of the bronchoscopic and microbiologic findings, we made the diagnosis of Aspergillus tracheobronchitis and initiated antifungal therapy. He showed gradual improvement in his symptoms and continued taking oral itraconazole for 6 months. Physicians should consider Aspergillus tracheobronchitis as a probable diagnosis in immunocompromised patients presenting with atypical respiratory symptoms and should try to establish a prompt diagnosis.
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KEYWORD
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Aspergillosis, Allergic Bronchopulmonary, Itraconazole, Bronchoscopydrome
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